Abstract: Benzo[c]coumarins and related fused coumarins were prepared by cyclization of various nucleophiles with 4-chlorocoumarins and by related syntheses. Suzuki-Miyaura reactions of coumarin-derived bis(triflates) result in formation of arylated coumarins with excellent regioselectivity which is controlled by electronic and steric features of the substrate.

Review: Synlett 2024, DOI: 10.1055/s-0042-1751556.

Period of investigation: 2001 - Today

Keywords: heterocycles; heterocyclic enamines; cyclizations; silyl enol ethers