5.6 Domino Reactions of 2-Isothiocyanatobenzonitrile
Abstract: 2-Isothiocyanatobenzonitrile (ITCB) and isocyanatobenzonitrile (ICB) represent versatile synthetic building blocks containing a nitrile and an isothiocyanate or an isocyanate function, respectively. Domino reactions of ITCB and ICB provide a convenient access to a variety of pharmacologically important heterocycles.
Review: Curr. Org. Chem. 2009, 13, 955-964.
Period of investigation: 2002 – 2009
Keywords: domino reactions; cyclizations; heterocycles