Abstract: The combination of Pd-catalyzed cross-coupling with CH-arylation reactions allow for the synthesis of various hetero-PAHs with interesting optical, electronic or pharmacological properties. Simple nitro-substituted heterocycles undergo Pd-catalyzed CH-arylation reactions with excellent regioselectivity.

Review: Synlett 2024, 35, 1844–1860, DOI: 10.1055/s-0042-1751540.

Period of investigation: 2011 - Today

Keywords: Pd catalysis; heterocycles