1.5 Cross-Coupling / Twofold C-N Coupling Reactions

Abstract: The combination of Pd-catalyzed C-C Cross-coupling with twofold C-N coupling reactions allows for the synthesis of a variety of various hetero-PAHs with interesting optical, electronic or pharmacological properties.

Review: Synlett 2022, 33, 1215-1226.

Period of investigation: 2012 - Today

Keywords: Pd-catalysis; heterocycles